111. Metabolic Determinants of Cancer Cell Sensitivity to Distinct Modes of Ferroptosis

​

Mariluz Soula, Ross A. Weber, Omkar Zilka, Hanan Alwaseem,Konnor La, Henrik Molina,

Javier Garcia-Bermudez,* Derek A. Pratt* & Kıvanç Birsoy*

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110. On the Products of Cholesterol Autoxidation in Phospholipid Bilayers and the

Formation of Secosterols Derived Therefrom 

​

Emily L. Schaefer, Nadia Zopyrus, Zosia A. M. Zielinski, Glenn A. Facey & Derek A. Pratt*

Angewandte Chemie International Edition 2020, 59, 2089-2094.

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109. Base-Promoted C-C Bond Activation Enables Radical Allylation with Homoallylic Alcohols

Maximilian Lübbesmeyer, Emily G. Mackay, Mark A. R. Raycroft, Jonas Elfert, Derek A. Pratt* & Armido Studer*

Journal of the American Chemical Society 2020, 142, 2609-2616.

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108. Synthesis of Vitisin A & D: Thermal Isomerization Enabled by a Persistent Radical Equilibrium

Kevin J. Romero, Mitchell H. Keylor, Markus Griesser, Xu Zhu, Ethan J. Strobel, Derek A. Pratt* & Corey R. J. Stephenson*

Journal of the American Chemical Society 2020, 142, Accepted Manuscript.

107. A Compendium of Kinetic Cell Death Modulatory Profiles Identifies Ferroptosis Regulators

Megan Conlon, Carson Poltorack, Giovanni Forcina, Alex Wells, Melodie Mallais, Alexis Kahanu, Leslie Magtanong,

Derek A. Pratt & Scott J. Dixon* 

Submitted (deposited on biorxiv at doi: https://doi.org/10.1101/826925).

​

106. Hydrogen Atom Abstraction from Polyolefins: Experimental and Computational Studies of Model Systems

​

Graham E. Garrett, Derek A. Pratt & J. Scott Parent*

Submitted

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104. FSP1 is a Glutathione-Independent Ferroptosis Suppressor

​

Sebastian Doll, Florencio Porto Freitas, Ron Shah, Maceler Aldrovandi, Milene Costa da Silva, Irina Ingold, Andrea Goya Grocin, Elena Panzilius, Christina Scheel, André Mourão, Katalin Buday, Jonas Wanninger, Thibaut Vignane, Vaishnavi Mohana, Markus Rehberg, Andrew Flatley, Aloys Schepers, Andreas Kurz, Daniel White, Markus Sauer, Michael Sattler, Edward William Tate, Werner Schmitz, Almut Schulze, Valerie O’Donnel, Bettina Proneth, Grzegorz M. Popowicz, Derek A. Pratt, José Pedro Friedmann Angeli* & Marcus Conrad*

Nature 2019, 575, 693-698.

(See related Nature News & Views on this manuscript)

105. The Chemical Basis of Ferroptosis 

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Marcus Conrad* & Derek A. Pratt*

Nature Chemical Biology 2019, 15, 1137-1147.

(Perspective)

103. Beyond DPPH: Use of Fluorescence-ENabled Inhibited AutoXidation (FENIX) Predicts Oxidative Cell Death Rescue

​

Ron Shah, Luke A. Farmer, Omkar Zilka, Antonius T. M. Van Kessel & Derek A. Pratt*

Cell Chemical Biology 2019, 26, 1594-1607.

(Selected as a feature article; see highlight 'Dawn of a New Era of Targeted Antioxidant Therapy' in Cell Chemical Biology)

102. Threshold Protective Effect of Deuterated Polyunsaturated Fatty Acids on the Peroxidation of Lipid Bilayers

Alexander M. Firsov, Maksim A. Fomich, Andrei V. Bekish, Olga L. Sharko, Elena A. Kotova, Harry J. Saal, Dragoslav Vidovic, Vadim V. Shmanai, Derek A. Pratt, Yuri N. Antonenko* & Mikhail S. Shchepinov*

FEBS Journal 2019, 286, 2099-2117.

101. The Antioxidant Activity of Polysulfides: It’s Radical!

​

Jean-Philippe R. Chauvin, Markus Griesser & Derek A. Pratt*

Chemical Science

2019, 10, 4999-5010.

(Selected as a 'Hot Article' and highlighted in RSC's Chemistry World)

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100. H-Atom Abstraction vs. Addition: Accounting for the Diverse Product Distribution in the Autoxidation of Cholesterol & its Esters

​

Zosia A. M. Zielinski & Derek A. Pratt*

Journal of the American Chemical Society 2019, 141, 3037-3051.