top of page
2022
2021
2020

Dearomative Dimerization of Quinolines and their Skeletal Rearrangement to Indoles

Triggered by Single-Electron Transfer

Eugene Yew Kun Tan, Alireza Dehdari, Amirah S. Mat Lani, Derek A. Pratt* & Shunsuke Chiba*

Submitted (click title to see preprint)

 

A Beginner's Guide to Ferroptosis

Toshitaka Nakamura, Eikan Mishima, Sebastian Doll, Koya Ono, Weijia Zhang, Anastasia Levkina, Mariia Novikova,

Jiashuo Zheng, Tobias Seibt, Maceler Aldrovandi, Svenja M. Lorenz, Junya Ito, Deng Chen,

Naoya Yamada, Golnaz Mardani, Chenxi Xu, Bernhard Henkelmann, Bettina Proneth, Maria Fedorova,

Derek A. Pratt, José Pedro Friedmann Angeli, Scott J. Dixon, Adam Wahida & Marcus Conrad*

Submitted

Sex-Specific Expression of Estradiol Derivatives, Hydropersulfides and Ether Lipids

Regulates Ferroptosis Sensitivity of Kidney Tubules 

Alexia Belavgeni, Wulf Tonnus, Francesca Maremonti, Sider Penkov, Melodie Mallais, Christine Gaillet, Anne Brucker, Danny Schilling, Lisa Schlicker, Nina Himmerkus, Shubhangi Gavali, Marlena Schlecht, Karolin Flade, Jorunn Naila Becker, Mirela Tmava, Anne Haag, Christian Hugo, Almut Schulze, Bernd Plietker, Jan Ulrich Becker, Joel M. Weinberg, Bettina Proneth, Marcus Conrad, Raphael Rodriguez, Stefan R. Bornstein, Tobias P. Dick, Derek A. Pratt, Maria Fedorova & Andreas Linkermann*

Submitted (click title to see preprint)

144. Ferroptosis in Health and Disease

Carsten Berndt, 92 authors... & Marcus Conrad*

Redox Biology 2024, 75, 103211

143. Reactions of Lipid Hydroperoxides and How They May Contribute to Ferroptosis Sensitivity

Dmitry D. Saraev & Derek A. Pratt*

Current Opinion in Chemical Biology 2024, 81,102478

142. Revisiting the Reactivity of the Dismissed Hydrogen Atom Transfer Catalyst Succinimide-N-oxyl 

Cheng Yang, Luke A. Farmer, Derek A. Pratt,* Stephen Maldonado,* & Corey R. J. Stephenson*

Journal of the American Chemical Society 2024146, 12511-12518

141. Non-Tertiary Alkyl Substituents Enhance High-Temperature Radical Trapping by

Phenothiazine and Phenoxazine Antioxidants

Luke A. Farmer & Derek A. Pratt*

Journal of Organic Chemistry 2024, 89, 6126–6137

140. Attenuating N-oxyl Decomposition for Improved Hydrogen Atom Transfer Catalysts Design

Cheng Yang, Luke A. Farmer, Elvis M. McFee, Rahul Jah, Stephen Maldonado,* Derek A. Pratt* & Corey R. J. Stephenson*

Angewandte Chemie International Edition 2024, 63, e202315917

139. 7-Dehydrocholesterol is an Endogenous Suppressor of Ferroptosis 

Florencio Porto Freitas, Hamed Alborzinia, Ancely Ferreira dos Santos, Palina Nepachalovich, Lohans P. Puentes, Omkar Zilka,

Alex Inague, Corinna Klein, Nesrine Aroua, Kamini Kaushal, Bettina Kast, Svenja M. Lorenz, Viktoria Kunz, Helene Nehring,

Thamara N. Xavier da Silva, Zhiyi Chen, Sena Atici, Sebastian G. Doll, Emily L. Schaefer, Ifedapo Ekpo, Werner Schmitz,

Aline Horling, Peter Imming, Sayuri Miyamoto, Ann Wehmann, Thiago C. Genaro-Mattos, Karoly Mirnics, Lokender Kumar,

Judith Klein-Seetharaman, Svenja Meierjohann, Isabel Weigand, Matthias Kroiss, Georg W. Bornkamm, Fernando Gomes,

Luis Eduardo Soares Netto, Manjima B. Sathian, David B. Konrad, Douglas F. Covey, Bernhard Michalke, Kurt Bommert,

Ralf C. Bargou, Ana Garcia-Saez, Derek A. Pratt, Maria Fedorova, Marcus Conrad & José Pedro Friedmann Angeli*

Nature 2024626, 401-410

138. Interrupted Homolytic Substitution Enables Organoboron Compounds to Inhibit Radical Chain

Reactions Rather than Initiate Them

Zijun Wu, Robynne Vlaming, Michael Donohoe & Derek A. Pratt* 

Journal of the American Chemical Society 2024, 146, 1153-1166

2023

137. Enhancement of Diarylamine Antioxidant Activity by Molybdenum Dithiocarbamates

Carly S. Hanson, Michael Donohoe & Derek A. Pratt* 

Journal of Organic Chemistry 2023, 88, 17420-17429

136. Photocatalytic C-S Bond Formation Using N-Thiophthalimide and N-Perthiophthalimide Derivatives

Hsin-Ju Huang, Zijun Wu & Derek A. Pratt* 

ACS Catalysis 202313, 13912-13919

135. Intramolecular H-Atom Transfers in Alkoxyl Radical Intermediates Underlie the

Apparent Oxidation of Lipid Hydroperoxides by Fe(II)

Dmitry D. Saraev, Zijun Wu, Hye-Young Kim, Ned A. Porter & Derek A. Pratt* 

ACS Chemical Biology 2023,18, 2073-2081

134. Leveraging the Persistent Radical Effect in the Synthesis of Trans-2,3-Diaryl-Dihydrobenzofurans

Bec J. Roldan, Travis A. Hammerstad, Matthew S. Galliher, Mitchell H. Keylor, Derek A. Pratt* & Corey R. J. Stephenson* 

Angewandte Chemie International Edition 2023, 62, e202305801

133. Development of PINO-Derived Hydrogen Atom Transfer Catalysts

Cheng Yang, Sahil Arora, Stephen Maldonado,* Derek A. Pratt* & Corey R. J. Stephenson* 

Nature Reviews Chemistry 2023, 7, 653-666

132. Targeting Lipoxygenases to Suppress Ferroptotic Cell Death

Derek A. Pratt* 

Proceedings of the National Academy of Sciences 2023120, e2309317120

(invited commentary)

 

131. Emergence of (Hydro)persulfides as Suppressors of Lipid Peroxidation and Ferroptotic Cell Death

Zijun Wu, Uladzimir Barayeu, Danny Schilling, Tobias P. Dick* & Derek A. Pratt*

Current Opinion in Chemical Biology 202376, 102353

(invited contribution to themed issue on the chemical biology of sulfur and selenium)

130. Radical Approaches to C-S Bonds

Zijun Wu & Derek A. Pratt* 

Nature Reviews Chemistry 2023, 7, 573-589

129. vPIF-1 is an Insulin-Like Anti-Ferroptotic Viral Peptide

Alexia Belavgeni, Francesca Maremonti, Wulf Tonnus, Marlena Stadtmüller, Shubhangi Gavali, Melodie Mallais, Karolin Flade,

Anne Brucker, Jorunn Naila Becker, Kristina Beer, Mirela Tmava, Julian Stumpf, Florian Gembardt, Christian Hugo, Mauro Giacca,

Benjamin G. Hale, Nikolaos Perakakis, Wei Sha, Derek A. Pratt, Andrew V. Schally, Stefan R. Bornstein* & Andreas Linkermann*

Proceedings of the National Academy of Sciences 2023,120, e2300320120

 

128. Ferroptosis: A Flexible Constellation of Related Biochemical Mechanisms

Scott J. Dixon* & Derek A. Pratt* 

Molecular Cell 2023, 83, 1030-1042

127. General Approach to Identify, Assess and Characterize Inhibitors of

Lipid Peroxidation and Associated Cell Death

Melodie Mallais, Carly S. Hanson, Melanie Giray & Derek A. Pratt* 

ACS Chemical Biology 2023, 18, 561-571

2022

126. Hydropersulfides Inhibit Lipid Peroxidation and Protect Cells From Ferroptosis

Zijun Wu, Vinayak S. Khodade, Jean-Philippe R. Chauvin, Deborah Rodriguez, John P. Toscano & Derek A. Pratt* 

Journal of the American Chemical Society 2022, 144, 15825-15837

(featured in Nature Chemical Biology ‘News and Views’ and a 'Spotlight' in Cell Chemical Biology)

125. Intrinsic & Extrinsic Limitations to the Design and Optimization of Inhibitors

of Lipid Peroxidation and Associated Cell Death

Luke A. Farmer, Zijun Wu, Jia-Fei Poon, Omkar Zilka, Svenja M. Lorenz, Stephanie Huehn,

Bettina Proneth, Marcus Conrad & Derek A. Pratt* 

Journal of the American Chemical Society 2022, 144, 14706-14721

124. A Non-Canonical Vitamin K Cycle is a Potent Ferroptosis Suppressor

Eikan Mishima,* Junya Ito, Zijun Wu, Toshitaka Nakamura, Sebastian Doll, Wulf Tonnus, Palina Nepachalovich, Elke Eggenhofer,

Maceler Aldrovandi, Bernhard Henkelmann, Ken-ichi Yamada, Jonas Wanninger, Adam Wahida, Omkar Zilka, Emiko Sato,

Regina Feederle, Daniela Hass, Adriano Maida, André Santos Dias Mourão, Andreas Linkermann, Edward K. Geissler,

Kiyotaka Nakagawa, Takaaki Abe, Maria Fedorova, Bettina Proneth, Derek A. Pratt & Marcus Conrad*

Nature 2022, 608, 778-783

(featured in Nature ‘News and Views’ and a 'Spotlight' in Molecular Cell)

 

123. Mechanism of Visible-Light Mediated Alkene Aminoarylation with Arylsulfonylacetamides

Anthony R. Allen, Jia-Fei Poon, Rory C. McAtee, Nicholas B. Watson, Derek A. Pratt* & Corey R.J. Stephenson*

ACS Catalysis 2022,12, 8511-8526

2021

122. The Radical-Trapping Antioxidant Activity of Copper and Nickel bis(Thiosemicarbazone) Complexes

Underlies Their Potency as Inhibitors of Ferroptotic Cell Death

Omkar Zilka, Jia-Fei Poon & Derek A. Pratt*

Journal of the American Chemical Society 2021, 143, 19043-19057

121. Temperature-Dependence of Radical-Trapping Activity of Phenoxazine, Phenothiazine and their

Aza-Analogues Clarifies the Way Forward for New Antioxidant Design

Jia-Fei Poon, Luke A. Farmer, Evan A. Haidasz & Derek A. Pratt*

Chemical Science 202112, 11065-11079

120. Dysfunction of the Key Ferroptosis-Surveilling Systems Hypersensitizes Mice to Massive

Tubular Necrosis During Acute Kidney Injury

Wulf Tonnus, Claudia Meyer, Christian Steinebach, Alexia Belavgeni, Anne von Mässenhausen, Nadia Zamora Gonzalez,

Florian Gembardt, Nina Himmerkus, Francesca Maremonti, Markus Latk, Sophie Locke, Sebastian Doll, Spencer Short, Irina Ingold, Bettina Proneth, Kerstin Amann, Christoph Daniel, Nazanin Kabgani, Rafael Kramann, Paul Hergenrother, Stefan R. Bornstein,

Christian Hugo, Jan Ulrich Becker, Michael Gütschow, Derek Pratt, Marcus Conrad & Andreas Linkermann*

Nature Communications 2021, 12, 4402

 

119. On the Mechanism of Electrochemical Generation and Decomposition of Phthalimide N-oxyl (PINO)

Cheng Yang, Luke A. Farmer, Derek A. Pratt,* Stephen Maldonado* & Corey R. J. Stephenson*

Journal of the American Chemical Society 2021, 143, 10324-10332

118. Autoxidation vs. Antioxidants - The Fight for Forever

Julian Helberg & Derek A. Pratt*

Chemical Society Reviews 202150, 7343-7358

(invited contribution to themed collection on radical chemistry)

117. A Divergent Strategy for Site-Selective Radical Disulfuration of Carboxylic Acids with Trisulfide-1,1-Dioxides

Zijun Wu & Derek A. Pratt*

Angewandte Chemie International Edition 2021, 60, 15598-15605

(highlighted in Synform)

116. Temperature-Dependent Effects of Alkyl Substitution on Diarylamine Radical-Trapping Antioxidant Activity 

Ron Shah, Jia-Fei Poon, Evan A. Haidasz & Derek A. Pratt*

Journal of Organic Chemistry 202186, 6538-6550

115. A Compendium of Cell Death Modulatory Profiles Identifies Ferroptosis Regulators

Megan Conlon, Carson Poltorack, Giovanni Forcina, Alex Wells, Melodie Mallais, Alexis Kahanu, Leslie Magtanong,

Derek A. Pratt & Scott J. Dixon*

Nature Chemical Biology 2021,17, 665-674

(highlighted in Nature Chemical Biology 'News and Views')

2020

114. Potent Ferroptosis Inhibitors Can Catalyze the Cross-Dismutation of Phospholipid-Derived

Alkylperoxyl Radicals and Hydroperoxyl Radicals

Jia-Fei Poon, Omkar Zilka & Derek A. Pratt*

Journal of the American Chemical Society 2020, 142, 14331-14342

113. Metabolic Determinants of Cancer Cell Sensitivity to Distinct Modes of Ferroptosis

Mariluz Soula, Ross A. Weber, Omkar Zilka, Hanan Alwaseem, Konnor La, Henrik Molina, Javier Garcia-Bermudez,*

Derek A. Pratt* & Kıvanç Birsoy*

Nature Chemical Biology 2020, 16, 1351-1360

112. Radical Substitution on Tetrasulfides: A Unique Route to Disulfides 

Zijun Wu & Derek A. Pratt*

Journal of the American Chemical Society 2020, 142, 10284-10290

111. Persistent Quinone Methide Dimers Lacking Labile H-Atoms Are Surprisingly Excellent

Radical-Trapping Antioxidants

Mark A. R. Raycroft, Jean-Philippe R. Chauvin, Matthew S. Galliher, Kevin J. Romero,

Corey R. J. Stephenson* & Derek A. Pratt*

Chemical Science 2020, 11, 5676-5689

(selected by the editors as a ‘Hot Article’ and ‘Pick of the Week’)

110. Reactive Sterol Electrophiles: Mechanisms of Formation and Reactions with

Proteins and Amino Acid Nucleophiles 

Ned A. Porter,* Libin Xu & Derek A. Pratt

Chemistry 2020, 2, 390-417

(invited contribution to themed issue in honour of Prof. Bernd Giese’s 80th birthday)

109. Hydrogen Atom Abstraction from Polyolefins: Experimental and Computational Studies of Model Systems

Graham E. Garrett, Derek A. Pratt & J. Scott Parent*

Macromolecules 2020, 53, 2793-2800

108. Synthesis of Vitisin A & D: Thermal Isomerization Enabled by a Persistent Radical Equilibrium 

Kevin J. Romero, Mitchell H. Keylor, Xu Zhu, Ethan J. Strobel,

Derek A. Pratt* & Corey R. J. Stephenson*

Journal of the American Chemical Society 2020, 142, 6499-6504

107. Base-Promoted C-C Bond Activation Enables Radical Allylation with Homoallylic Alcohols

Maximilian Lübbesmeyer, Emily G. Mackay, Mark A. R. Raycroft, Jonas Elfert, Derek A. Pratt* & Armido Studer*

Journal of the American Chemical Society 2020, 142, 2609-2616

106. On the Products of Cholesterol Autoxidation in Phospholipid Bilayers and the Formation of

Secosterols Derived Therefrom 

Emily L. Schaefer, Nadia Zopyrus, Zosia A. M. Zielinski & Derek A. Pratt*

Angewandte Chemie International Edition 2020, 59, 2089-2094

(selected by the editors as a ‘Very Important Paper’)

2019

105. The Chemical Basis of Ferroptosis

Marcus Conrad* & Derek A. Pratt*

Nature Chemical Biology 2019, 15, 1137-1147

(commissioned ‘Perspective’; highlighted in MedicalXpress)

104. FSP1 is a Glutathione-Independent Ferroptosis-Suppressor

Sebastian Doll, Florencio Porto Freitas, Ron Shah, Milene Costa da Silva, Irina Ingold, Andrea Goya Grocin, Elena Panzilius, Christina Scheel, Katalin Buday, Jonas Wanninger, Thibaut Vignane, Vaishnavi Mohana, Van Lam, Aloys Schepers, Valerie O’Donnel, Maceler Aldrovandi, Michael Sattler, Edward William Tate, Bettina Proneth, Werner Schmitz, Almut Schulze, Gregorz Popowicz,

Derek A. Pratt, José Pedro Friedmann Angeli,* Marcus Conrad*

Nature 2019, 575, 693-698

(featured in Nature ‘News and Views’ and highlighted in Nature Chemical Biology)

103. Beyond DPPH: Use of Fluorescence-ENabled Inhibited AutoXidation (FENIX) to Predict

Oxidative Cell Death Rescue

Ron Shah, Luke Farmer, Omkar Zilka, Anthony T. M. Van Kessel & Derek A. Pratt*

Cell Chemical Biology 2019, 26, 1594-1607

(selected as a ‘Feature Article’ and highlighted in Cell Chem. Biol.)

102. Threshold Protective Effect of Deuterated Polyunsaturated Fatty Acids on the Peroxidation of Lipid Bilayers

Alexander M. Firsov, Maksim A. Fomich, Andrei V. Bekish, Olga L. Sharko, Elena A. Kotova, Harry J. Saal, Dragoslav Vidovic,

Vadim V. Shmanai, Derek A. Pratt, Yuri N. Antonenko* & Mikhail S. Shchepinov*

FEBS J. 2019, 286, 2099-2017

101. The Antioxidant Activity of Polysulfides: It’s Radical!

Jean-Philippe R. Chauvin, Markus Griesser & Derek A. Pratt*

Chemical Science 2019, 10, 4999-5010 

(selected as a ‘Hot Article’ and highlighted in the Royal Society of Chemistry’s Chemistry World)

100. H-Atom Abstraction vs. Addition: Accounting for the Diverse Product Distribution in the

Autoxidation of Cholesterol & its Esters

Zosia A. M. Zielinski & Derek A. Pratt*

Journal of the American Chemical Society 2019, 141, 3037-3051

2018

99. Electrochemical Dimerization of Phenylpropenoids and the Surprising Antioxidant Activity of the

Resultant Quinone Methide Dimers

Kevin J. Romero, Matthew S. Galliher, Irene Bosque, Mark A. R. Raycroft, Jean-Philippe R. Chauvin,

Derek A. Pratt* & Corey R. J. Stephenson*

Angewandte Chemie International Edition 2018, 57, 17125-17129

98. Radicals in Natural Product Synthesis

Kevin J. Romero, Matthew S. Galliher, Derek A. Pratt* & Corey R. J. Stephenson*

Chemical Society Reviews 2018, 47, 7851-7866

(invited tutorial review)

 

97. Recent Insights on Hydrogen Atom Transfer in the Inhibition of Hydrocarbon Autoxidation

Jia-Fei Poon & Derek A. Pratt*

Accounts of Chemical Research 2018, 51, 1996-2005

(invited for special issue on H-atom transfer)

96. The Hydrogen Atom Transfer Reactivity of Sulfinic Acids

Markus Griesser, Jean-Philippe R. Chauvin & Derek A. Pratt*

Chemical Science 2018, 9, 7218-7229

95. Inhibition of Hydrocarbon Autoxidation by Nitroxide-Catalyzed Cross-Dismutation of

Hydroperoxyl and Alkylperoxyl Radicals 

Kareem A. Harrison, Evan A. Haidasz, Markus Griesser & Derek A. Pratt*

Chemical Science 2018, 9, 6068-6079

 

94. The Catalytic Reaction of Nitroxides with Peroxyl Radicals its Relevance to their Cytoprotective Properties 

Markus Griesser, Ron Shah, Antonius T. M. Van Kessel, Omkar Zilka, Evan A. Haidasz & Derek A. Pratt*

Journal of the American Chemical Society 2018, 140, 3798-3808

93. Resolving the Role of Lipoxygenases in the Initiation and Execution of Ferroptosis

Ron Shah, Mikhail S. Shchepinov & Derek A. Pratt*

ACS Central Science 2018, 4, 387-396

(selected for an ACS Central Science ‘First Reaction’)

2019
2018
2023
2017
2016

2017

92. Phenoxazine: A Privileged Scaffold for Radical-Trapping Antioxidants

Luke Farmer, Evan A. Haidasz, Markus Griesser & Derek A. Pratt*

Journal of Organic Chemistry 2017, 82, 10523-10536

91. The Potency of Diarylamine Radical-Trapping Antioxidants as Inhibitors of Ferroptosis Underscores

the Role of Autoxidation in Cell Death

Ron Shah, Kaitlyn D. Margison & Derek A. Pratt*

ACS Chemical Biology 201712, 2538-2545

90. Hydroperosulfides: H-atom Transfer Agents Par Excellence

Jean-Philippe R. Chauvin, Markus Griesser & Derek A. Pratt*

Journal of the American Chemical Society 2017, 139, 6484-6493

(selected for a JACS ‘Spotlight’)

89. Diazaphenoxazines and Diazaphenothiazines: Synthesis of the ‘Correct’ Isomers Reveals They are

Highly Reactive Radical-Trapping Antioxidants

Evan A. Haidasz & Derek A. Pratt*

Organic Letters 2017, 19, 1854-1857

88. Lipid Peroxidation: Kinetics, Mechanisms and Products

Zosia A. M. Zielinski & Derek A. Pratt*

Journal of Organic Chemistry 2017, 82, 2817-2825

(invited ‘Synopsis’)

87. Aminyl Radical Generation via Tandem Norrish Type I Photocleavage, b-Fragmentation:

Independent Generation and Reactivity of the 2'-Deoxyadenosin-N6-yl Radical 

Liwei Zheng, Markus Griesser, Derek A. Pratt* & Marc M. Greenberg*

Journal of Organic Chemistry 2017, 82, 3571-3580

86. Ferroptosis Inhibition: Mechanisms and Opportunities 

José Pedro Friedmann Angeli,* Ron Shah, Derek A. Pratt & Marcus Conrad

Trends in Pharmaceutical Sciences 2017, 38, 489-498

85. The Radical-Trapping Antioxidant Activity of Ferrostatin-1 and Liproxstatin-1 Suggests that

Lipid Peroxidation (Autoxidation) Drives Ferroptotic Cell Death

Omkar Zilka, Ron Shah, Bo Li, José Pedro Friedmann Angeli, Markus Griesser, Marcus Conrad & Derek A. Pratt*

ACS Central Science 2017, 3, 232-243

(highlighted in Cell Chemical Biology)

84. On the Mechanism of Thiol, Sulfenic and Sulfinic Acid Oxidation by Hydrogen Peroxide

Jean-Philippe R. Chauvin & Derek A. Pratt*

Angewandte Chemie International Edition 2017, 56, 6255-6259

(highlighted in Nature Reviews Chemistry)

 

2016

83. Synthesis of Resveratrol Tetramers via a Stereoconvergent Radical Equilibrium

Mitchell H. Keylor, Bryan S. Matsuura, Markus Griesser, Jean-Philippe R. Chauvin, Ryan A. Harding,

Mariia S. Kirillova, Oliver J. Fischer, Derek A. Pratt* & Corey R. J. Stephenson*

Science 2016, 354, 1260-1265

(highlighted in the American Chemical Society’s Chemical & Engineering News) 

82. Rapid Determination of Key Hydrocarbon Autoxidation Products by Fluorescence

Ron Shah & Derek A. Pratt*

Journal of Organic Chemistry 2016, 81, 6649-6656

81. Polysulfide-1-Oxides React with Peroxyl Radicals as Quickly as Hindered Phenolic Antioxidants and

Do So By a Surprising Concerted Homolytic Substitution 

Jean-Philippe R. Chauvin, Evan A. Haidasz, Markus Griesser & Derek A. Pratt*

Chemical Science 2016, 7, 6347-6356

80. Cholesterol Autoxidation Revisited: Debunking the Dogma Associated with the Most Vilified of Lipids

Zosia Zielinski & Derek A. Pratt*

Journal of the American Chemical Society 2016, 138, 6932-6935

(selected for a JACS ‘Spotlight’; selected as one of twelve ‘JACS Editors’ Choice’ articles for 2016)

79. Acid is Key to the Radical-Trapping Antioxidant Activity of Nitroxides

Evan A. Haidasz, Derek Meng, Riccardo Amorati, Keith U. Ingold, Luca Valgimigli* & Derek A. Pratt*

Journal of the American Chemical Society 2016, 138, 5290-5298

78. A Continuous Visible Light Spectrophotometric Approach to Accurately Determine the Reactivity of

Radical-Trapping Antioxidants 

Evan A. Haidasz, Antonius T. M. Van Kessel & Derek A. Pratt*

Journal of Organic Chemistry 2016, 81, 737-744

(selected as a ‘Featured Article’ and ‘Cover Article’)

77. Inspired by Garlic: Insights on the Chemistry of Sulfenic Acids and the Radical-Trapping Antioxidant Activity of

Organsulfur Compounds

Jean-Philippe R. Chauvin, Zosia Zielinski & Derek A. Pratt*

Canadian Journal of Chemistry 2016, 94, 1-8

(invited minireview in recognition of the 2015 CSC Fagnou Award in Organic Chemistry) 

2015

76. Molecular Mechanisms of the Medicinal Thiosulfinates from Garlic and Anamu:

They Are Not Radical-Trapping Antioxidants 

Bo Li, Feng Zheng, Jean-Philippe R. Chauvin & Derek A. Pratt*

Chemical Science 2015, 6, 6165-6178

(highlighted in the Royal Society of Chemistry’s Chemistry World)

75. Maximizing the Reactivity of Phenolic and Aminic Radical-Trapping Antioxidants: Just Add Nitrogen!

Luca Valgimigli* & Derek A. Pratt*

Accounts of Chemical Research 2015, 48, 966-975

(invited review)

74. Determining the Efficacy of Radical-Trapping Antioxidants

Bo Li & Derek A. Pratt*

Free Radical Biology and Medicine 2015, 82, 187-202 

(invited review)

73. Unprecedented Inhibition of Hydrocarbon Autoxidation by Diarylamine Radical-Trapping Antioxidants

Ron Shah, Evan A. Haidasz, Luca Valgimigli & Derek A. Pratt*

Journal of the American Chemical Society 2015, 137, 2440-2443 

(selected for a JACS ‘Spotlight’)

72. A Scalable Biomimetic Synthesis of Resveratrol and Systematic Evaluation of their Antioxidant Activities

Byran S. Matsuura, Mitchell H. Keylor, Bo Li, YuXuan Lin, Shelby Allison, Derek A. Pratt* & Corey R. J. Stephenson*

Angewandte Chemie International Edition 2015, 54, 3754-3757

(selected as a ‘Hot Article’; highlighted in Nature Chemistry)

2015
bottom of page